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• Data ( » All » Frozen Pages » Data )
  • Age at onset as stratifier in idiopathic Parkinson's disease – effect of ageing and polygenic risk score on clinical phenotypes
  • ENA Dataset for Systematic characterization of human gut microbiome-secreted molecules by integrated multi-omics study
  • Metadata for the RESOLUTE project in the IMI Data Catalog
  • PRECISESADS: Molecular reclassification to find clinically useful biomarkers for systemic autoimmune diseases
• Manuscript ( » All » Frozen Pages » Manuscript )
  • Body-first subtype of Parkinson's disease with probable REM-sleep behaviour disorder is associated with non-motor dominant phenotype
  • COBREXA.jl: constraint-based reconstruction and exascale analysis
  • ChemPert: mapping between chemical perturbation and transcriptional response for noncancer cells
  • Clustering and visualizing huge-scale cytometry datasets with GigaSOM.jl
  • Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampus
  • Dibac: Distribution-Based Analysis Of Cell Differentiation Identifies Mechanisms Of Cell Fate
  • Functional meta-omics provide critical insights into long and short read assemblies
  • Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A>G (p.T351A) or c.2067A>G (p.T610A) in the RHOT1 gene encoding Miro1
  • Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1
  • IMP: a pipeline for reproducible reference-independent integrated metagenomic and metatranscriptomic analyses
  • Ice Recrystallization Inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis
  • Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
  • Machine learning-assisted neurotoxicity prediction in human midbrain organoids
  • Method optimization of skin biopsy-derived fibroblast culture for reprogramming into induced pluripotent stem cells (iPSCs)
  • Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
  • Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-G2019S - associated gene expression
  • Mitochondrial morphology provides a mechanism for energy buffering at synapses
  • Modeling Parkinson's disease in midbrain-like organoids
  • NORMAN Guidance on Suspect and Non-Target Screening in Environmental Monitoring
  • PaFSe: a Parameter Free Segmentation Approach for 3D Fluorescent Images
  • Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐Cyclodextrin Treatment
  • Passive controlled flow for neuronal cell culture in 3D microfluidic devices
  • Penalised regression with multiple sources of prior effects
  • Per- and polyfluoroalkyl substances (PFAS) in PubChem: 7 million and growing
  • Polarization of multi-agent gradient flows over manifolds with application to opinion dynamics
  • Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson's disease
  • Retrograde procedural memory in Parkinson's disease: a cross-sectional, case-control study
  • Retrospective Non-target Analysis to Support Regulatory Water Monitoring: From Masses of Interest to Recommendations via in silico workflows
  • SMASCH: multi-appointment scheduling system for longitudinal clinical research studies
  • Single cell transcriptomics of human iPSC differentiation dynamics reveal a core network of Parkinson’s disease
  • Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
  • Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
  • Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene
  • The Parkinson's disease associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
  • Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis in UK Biobank and Taiwan Biobank
  • Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson’s Disease Point Mutation A30P
• Other ( » All » Frozen Pages » Other )
  • Meta-analysis of gender-dependent gene expression alterations in Parkinson's disease
  • Seizure-induced increase in microglial cell population in the developing zebrafish brain
• 2016 ( » All » Frozen Pages » 2016 )
  • October 2016 ( » All » Frozen Pages » 2016 » October 2016 )
    • IMP: a pipeline for reproducible reference-independent integrated metagenomic and metatranscriptomic analyses
• 2019 ( » All » Frozen Pages » 2019 )
  • February 2019 ( » All » Frozen Pages » 2019 » February 2019 )
    • Modeling Parkinson's disease in midbrain-like organoids
  • March 2019 ( » All » Frozen Pages » 2019 » March 2019 )
    • Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
  • May 2019 ( » All » Frozen Pages » 2019 » May 2019 )
    • Mitochondrial morphology provides a mechanism for energy buffering at synapses
  • September 2019 ( » All » Frozen Pages » 2019 » September 2019 )
    • Machine learning-assisted neurotoxicity prediction in human midbrain organoids
    • Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
  • October 2019 ( » All » Frozen Pages » 2019 » October 2019 )
    • Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson's disease
• 2020 ( » All » Frozen Pages » 2020 )
  • January 2020 ( » All » Frozen Pages » 2020 » January 2020 )
    • Passive controlled flow for neuronal cell culture in 3D microfluidic devices
  • March 2020 ( » All » Frozen Pages » 2020 » March 2020 )
    • Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson’s Disease Point Mutation A30P
  • April 2020 ( » All » Frozen Pages » 2020 » April 2020 )
    • Clustering and visualizing huge-scale cytometry datasets with GigaSOM.jl
  • August 2020 ( » All » Frozen Pages » 2020 » August 2020 )
    • PaFSe: a Parameter Free Segmentation Approach for 3D Fluorescent Images
  • October 2020 ( » All » Frozen Pages » 2020 » October 2020 )
    • Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐Cyclodextrin Treatment
  • December 2020 ( » All » Frozen Pages » 2020 » December 2020 )
    • Metadata for the RESOLUTE project in the IMI Data Catalog
    • PRECISESADS: Molecular reclassification to find clinically useful biomarkers for systemic autoimmune diseases
• 2021 ( » All » Frozen Pages » 2021 )
  • February 2021 ( » All » Frozen Pages » 2021 » February 2021 )
    • Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
    • Retrograde procedural memory in Parkinson's disease: a cross-sectional, case-control study
  • March 2021 ( » All » Frozen Pages » 2021 » March 2021 )
    • Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
    • Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-G2019S - associated gene expression
    • Retrospective Non-target Analysis to Support Regulatory Water Monitoring: From Masses of Interest to Recommendations via in silico workflows
  • May 2021 ( » All » Frozen Pages » 2021 » May 2021 )
    • COBREXA.jl: constraint-based reconstruction and exascale analysis
    • Method optimization of skin biopsy-derived fibroblast culture for reprogramming into induced pluripotent stem cells (iPSCs)
  • July 2021 ( » All » Frozen Pages » 2021 » July 2021 )
    • Functional meta-omics provide critical insights into long and short read assemblies
    • Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene
  • August 2021 ( » All » Frozen Pages » 2021 » August 2021 )
    • Dibac: Distribution-Based Analysis Of Cell Differentiation Identifies Mechanisms Of Cell Fate
  • September 2021 ( » All » Frozen Pages » 2021 » September 2021 )
    • Single cell transcriptomics of human iPSC differentiation dynamics reveal a core network of Parkinson’s disease
    • The Parkinson's disease associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
  • November 2021 ( » All » Frozen Pages » 2021 » November 2021 )
    • Meta-analysis of gender-dependent gene expression alterations in Parkinson's disease
  • December 2021 ( » All » Frozen Pages » 2021 » December 2021 )
    • Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampus
• 2022 ( » All » Frozen Pages » 2022 )
  • April 2022 ( » All » Frozen Pages » 2022 » April 2022 )
    • Age at onset as stratifier in idiopathic Parkinson's disease – effect of ageing and polygenic risk score on clinical phenotypes
  • May 2022 ( » All » Frozen Pages » 2022 » May 2022 )
    • ChemPert: mapping between chemical perturbation and transcriptional response for noncancer cells
    • SMASCH: multi-appointment scheduling system for longitudinal clinical research studies
  • July 2022 ( » All » Frozen Pages » 2022 » July 2022 )
    • Body-first subtype of Parkinson's disease with probable REM-sleep behaviour disorder is associated with non-motor dominant phenotype
    • ENA Dataset for Systematic characterization of human gut microbiome-secreted molecules by integrated multi-omics study
  • September 2022 ( » All » Frozen Pages » 2022 » September 2022 )
    • Ice Recrystallization Inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis
  • November 2022 ( » All » Frozen Pages » 2022 » November 2022 )
    • Penalised regression with multiple sources of prior effects
• 2023 ( » All » Frozen Pages » 2023 )
  • February 2023 ( » All » Frozen Pages » 2023 » February 2023 )
    • Seizure-induced increase in microglial cell population in the developing zebrafish brain
  • May 2023 ( » All » Frozen Pages » 2023 » May 2023 )
    • Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1
    • Visualization of automatically combined disease maps and pathway diagrams for rare diseases
  • July 2023 ( » All » Frozen Pages » 2023 » July 2023 )
    • Defects in Miro1 cause impaired mitochondrial homeostasis and degeneration of human and murine dopaminergic neurons in vitro and in vivo
    • NORMAN Guidance on Suspect and Non-Target Screening in Environmental Monitoring
    • Per- and polyfluoroalkyl substances (PFAS) in PubChem: 7 million and growing
    • Polarization of multi-agent gradient flows over manifolds with application to opinion dynamics
    • SinCMat : A single-cell based method for predicting maturation transcription factors
    • Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis in UK Biobank and Taiwan Biobank
  • August 2023 ( » All » Frozen Pages » 2023 » August 2023 )
    • Federated Electronic Health Records for the European Health Data Space: An architecture proposal to break the privacy-exploitation barrier
    • Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A>G (p.T351A) or c.2067A>G (p.T610A) in the RHOT1 gene encoding Miro1
    • Genetic landscape of Parkinson’s disease in Luxembourg
    • Non-Target Screening of Surface Water Samples to Identify Exposome-Related Pollutants: A Case Study from Luxembourg
  • September 2023 ( » All » Frozen Pages » 2023 » September 2023 )
    • Impaired dopaminergic neuronal differentiation in GBA associated Parkinson’s disease midbrain organoids is accompanied by an increased progenitor pool in cell cycle arrest
    • Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
    • Omics data integration suggests a potential idiopathic Parkinson’s disease signature
    • Predictive Models for Health Deterioration: Understanding Disease Pathways for Personalized Medicine
  • November 2023 ( » All » Frozen Pages » 2023 » November 2023 )
    • The SYSCID map: a graphical and computational resource of molecular mechanisms across rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease
• 2024 ( » All » Frozen Pages » 2024 )
  • February 2024 ( » All » Frozen Pages » 2024 » February 2024 )
    • Alpha-synuclein pathology is associated with astrocyte senescence in Parkinson’s disease patient-specific midbrain organoids
  • April 2024 ( » All » Frozen Pages » 2024 » April 2024 )
    • Insulin resistance compromises midbrain organoid neural activity and metabolic efficiency predisposing to Parkinson’s disease pathology
    • Insulin resistance is a modifying factor for Parkinson's disease
  • October 2024 ( » All » Frozen Pages » 2024 » October 2024 )
    • Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes